PDB entry 4iqt

View 4iqt on RCSB PDB site
Description: Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
Class: transferase/transferase inhibitor
Keywords: terminal transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-01-13, released 2013-09-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-26, with a file datestamp of 2017-07-21.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA nucleotidylexotransferase
    Species: Mus musculus [TaxId:10090]
    Gene: DNTT, TDT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4iqta1, d4iqta2, d4iqta3
  • Heterogens: 1FO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4iqtA (A:)
    hmspspvpgsqnvpapavkkisqyacqrrttlnnynqlftdaldilaendelrenegscl
    afmrassvlkslpfpitsmkdtegipclgdkvksiiegiiedgesseakavlnderyksf
    klftsvfgvglktaekwfrmgfrtlskiqsdkslrftqmqkagflyyedlvscvnrpeae
    avsmlvkeavvtflpdalvtmtggfrrgkmtghdvdflitspeatedeeqqllhkvtdfw
    kqqglllycdilestfekfkqpsrkvdaldhfqkcflilkldhgrvhseksgqqegkgwk
    airvdlvmcpydrrafallgwtgsrqferdlrryatherkmmldnhalydrtkrvfleae
    seeeifahlgldyiepwernamgsshhhhhhssglvprgs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iqtA (A:)
    kisqyacqrrttlnnynqlftdaldilaendelrenegsclafmrassvlkslpfpitsm
    kdtegipclgdkvksiiegiiedgesseakavlnderyksfklftsvfgvglktaekwfr
    mgfrtlskiqsdkslrftqmqkagflyyedlvscvnrpeaeavsmlvkeavvtflpdalv
    tmtggfrrgkmtghdvdflitspeatedeeqqllhkvtdfwkqqglllycdilestfekf
    kqpsrdaldhfqkcflilkldhgrvhsekegkgwkairvdlvmcpydrrafallgwtgsr
    qferdlrryatherkmmldnhalydrtkrvfleaeseeeifahlgldyiepwerna