PDB entry 4iqk

View 4iqk on RCSB PDB site
Description: Crystal structure of cpd 16 bound to Keap1 Kelch domain
Class: transcription
Keywords: transcription
Deposited on 2013-01-11, released 2013-05-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: 0.155
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: INRF2, KEAP1, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14145 (Start-298)
      • conflict (38)
      • engineered mutation (229)
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4iqka_
  • Heterogens: IQK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iqkA (A:)
sglvprgshmapkvgrliytaggyfrqslsyleaynpsngtwlrladlqvprsglagcvv
ggllyavggrnnspdgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavgg
shgcihhnsveryeperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecy
ypernewrmitamntirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapm
khrrsalgitvhqgriyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

    Sequence, based on observed residues (ATOM records): (download) 
    >4iqkA (A:)
grliytaggyfrqslsyleaynpsngtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt