PDB entry 4iqa

View 4iqa on RCSB PDB site
Description: Crystal Structure Analysis of the E228L Mutant of Human CLIC1
Class: transport protein
Keywords: CLIC; Glutathione Transferase; pH salt bridge ion channel, TRANSPORT PROTEIN
Deposited on 2013-01-11, released 2013-02-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-02-20, with a file datestamp of 2013-02-15.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: 0.248
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chloride intracellular channel protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIC1, G6, NCC27
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00299 (0-End)
      • engineered mutation (222)
    Domains in SCOPe 2.07: d4iqaa1, d4iqaa2
  • Chain 'B':
    Compound: chloride intracellular channel protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIC1, G6, NCC27
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00299 (0-End)
      • engineered mutation (222)
    Domains in SCOPe 2.07: d4iqab1, d4iqab2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4iqaA (A:)
    pqvelfvkagsdgakigncpfsqrlfmvlwlkgvtfnvttvdtkrrtetvqklcpggqlp
    fllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayiknsnpal
    ndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnllpklh
    ivqvvckkyrgftipeafrgvhrylsnayareefastcpddelielayeqvakalk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iqaA (A:)
    pqvelfvkagsdgakigncpfsqrlfmvlwlkgvtfnvttvdtkrrtetvqklcpggqlp
    fllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayiknsnpal
    ndnlekgllkalkvldnyltsplpeevrkfldgneltladcnllpklhivqvvckkyrgf
    tipeafrgvhrylsnayareefastcpddelielayeqvakal
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4iqaB (B:)
    pqvelfvkagsdgakigncpfsqrlfmvlwlkgvtfnvttvdtkrrtetvqklcpggqlp
    fllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayiknsnpal
    ndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnllpklh
    ivqvvckkyrgftipeafrgvhrylsnayareefastcpddelielayeqvakalk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iqaB (B:)
    pqvelfvkagsdgakigncpfsqrlfmvlwlkgvtfnvttvdtkrrtetvqklcpggqlp
    fllygtevhtdtnkieefleavlcpprypklaalnpesntagldifakfsayiknsnpal
    ndnlekgllkalkvldnyltsplprkfldgneltladcnllpklhivqvvckkyrgftip
    eafrgvhrylsnayareefastcpddelielayeqvakal