PDB entry 4io0

View 4io0 on RCSB PDB site
Description: Crystal structure of F128A mutant of an epoxide hydrolase from Bacillus megaterium complexed with its product (R)-3-[1]naphthyloxy-propane-1,2-diol
Class: hydrolase
Keywords: a/b hydrolase fold, epoxide hydrolase, hydrolase
Deposited on 2013-01-07, released 2014-02-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-11-19, with a file datestamp of 2014-11-14.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.16
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Soluble epoxide hydrolase
    Species: Bacillus megaterium [TaxId:1404]
    Database cross-references and differences (RAF-indexed):
    • Uniprot G9BEX6 (17-303)
      • expression tag (16)
      • engineered mutation (144)
    Domains in SCOPe 2.06: d4io0a1, d4io0a2
  • Chain 'B':
    Compound: Soluble epoxide hydrolase
    Species: Bacillus megaterium [TaxId:1404]
    Database cross-references and differences (RAF-indexed):
    • Uniprot G9BEX6 (Start-303)
      • engineered mutation (144)
    Domains in SCOPe 2.06: d4io0b_
  • Heterogens: SO4, RN1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4io0A (A:)
gshmasmtggqqmgrgsmskqyinvngvnlhyiskgqgelmlflhgfpdfshiwrhqide
fsndfhtvaldlrgynlsekpsglesyeidvlvedirqvieglgyssctlvvhdwgagig
wtfayrypeyvqkliafngphpytamrelrtnknqqkaseymkwfqkqevqdymerdnfs
glrklvidpgvkkgyltaddvqaymnswengsvlsmlsyyrnlkifteedlrrkslfple
eevlnipvqiiwgnqdptfmpenldgieeyvpnisvhrlaeashapqhekpqevnnvmwn
flnk

    Sequence, based on observed residues (ATOM records): (download) 
    >4io0A (A:)
smskqyinvngvnlhyiskgqgelmlflhgfpdfshiwrhqidefsndfhtvaldlrgyn
lsekpsglesyeidvlvedirqvieglgyssctlvvhdwgagigwtfayrypeyvqklia
fngphpytamrelrtnknqqkaseymkwfqkqevqdymerdnfsglrklvidpgvkkgyl
taddvqaymnswengsvlsmlsyyrnlkifteedlrrkslfpleeevlnipvqiiwgnqd
ptfmpenldgieeyvpnisvhrlaeashapqhekpqevnnvmwnflnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4io0B (B:)
gshmasmtggqqmgrgsmskqyinvngvnlhyiskgqgelmlflhgfpdfshiwrhqide
fsndfhtvaldlrgynlsekpsglesyeidvlvedirqvieglgyssctlvvhdwgagig
wtfayrypeyvqkliafngphpytamrelrtnknqqkaseymkwfqkqevqdymerdnfs
glrklvidpgvkkgyltaddvqaymnswengsvlsmlsyyrnlkifteedlrrkslfple
eevlnipvqiiwgnqdptfmpenldgieeyvpnisvhrlaeashapqhekpqevnnvmwn
flnk

    Sequence, based on observed residues (ATOM records): (download) 
    >4io0B (B:)
qyinvngvnlhyiskgqgelmlflhgfpdfshiwrhqidefsndfhtvaldlrgynlsek
psglesyeidvlvedirqvieglgyssctlvvhdwgagigwtfayrypeyvqkliafngp
hpytamrelrtnknqqkaseymkwfqkqevqdymerdnfsglrklvidpgvkkgyltadd
vqaymnswengsvlsmlsyyrnlkifteedlrrkslfpleeevlnipvqiiwgnqdptfm
penldgieeyvpnisvhrlaeashapqhekpqevnnvmwnflnk