PDB entry 4ijx
View 4ijx on RCSB PDB site
Description: Crystal structure of human Ap4A hydrolase E58A mutant complexed with DPO
Class: hydrolase
Keywords: nudix fold, hydrolase
Deposited on
2012-12-24, released
2013-03-20
The last revision prior to the SCOPe 2.07 freeze date was dated
2013-03-20, with a file datestamp of
2013-03-15.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.191
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Species: Homo sapiens [TaxId:9606]
Gene: NUDT2, APAH1
Database cross-references and differences (RAF-indexed):
- Uniprot P50583 (Start-146)
- engineered mutation (57)
- expression tag (147-149)
Domains in SCOPe 2.07: d4ijxa1, d4ijxa2 - Chain 'B':
Compound: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Species: Homo sapiens [TaxId:9606]
Gene: NUDT2, APAH1
Database cross-references and differences (RAF-indexed):
- Uniprot P50583 (Start-146)
- engineered mutation (57)
- expression tag (147)
Domains in SCOPe 2.07: d4ijxb1, d4ijxb2 - Heterogens: MG, DPO, GOL, PO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4ijxA (A:)
malracgliifrrclipkvdnnaieflllqasdgihhwtppkghvepgeddletalratq
eeagieagqltiiegfkrelnyvarnkpktviywlaevkdydveirlshehqayrwlgle
eacqlaqfkemkaalqeghqflcsiealehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4ijxA (A:)
racgliifrrclipkvdnnaieflllqasdgihhwtppkghvepgeddletalratqeea
gieagqltiiegfkrelnyvarnkpktviywlaevkdydveirlshehqayrwlgleeac
qlaqfkemkaalqeghqflcsiealeh
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4ijxB (B:)
malracgliifrrclipkvdnnaieflllqasdgihhwtppkghvepgeddletalratq
eeagieagqltiiegfkrelnyvarnkpktviywlaevkdydveirlshehqayrwlgle
eacqlaqfkemkaalqeghqflcsiealehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4ijxB (B:)
lracgliifrrclipknaieflllqasdgihhwtppkghvepgeddletalratqeeagi
eagqltiiegfkrelnyvarnkpktviywlaevkdydveirlshehqayrwlgleeacql
aqfkemkaalqeghqflcsieal