PDB entry 4ijl

View 4ijl on RCSB PDB site
Description: Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A
Class: DNA binding protein/inhibitor
Keywords: OB-Fold, Protein-Protein Interaction, DNA BINDING PROTEIN-INHIBITOR complex
Deposited on 2012-12-21, released 2013-08-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-08-14, with a file datestamp of 2013-08-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.193
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replication protein A 70 kDa DNA-binding subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: REPA1, RPA1, RPA70
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27694 (3-122)
      • expression tag (1-2)
      • engineered mutation (9)
    Domains in SCOPe 2.06: d4ijla1, d4ijla2
  • Heterogens: 1EK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ijlA (A:)
gshmvgqlsrgaiaaimqkgdtnikpilqvinirpittgnsppryrllmsdglntlssfm
latqlnplveeeqlssncvcqihrfivntlkdgrrvvilmelevlksaeavgvkignpvp
yne

    Sequence, based on observed residues (ATOM records): (download) 
    >4ijlA (A:)
shmvgqlsrgaiaaimqkgdtnikpilqvinirpittgnsppryrllmsdglntlssfml
atqlnplveeeqlssncvcqihrfivntlkdgrrvvilmelevlksaeavgvkignpvpy
ne