PDB entry 4iin

View 4iin on RCSB PDB site
Description: Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695 complexed with NAD+
Class: oxidoreductase
Keywords: structural genomics, Center for Structural Genomics of Infectious Diseases, CSGID, short chain dehydrogenase, FabG, beta-ketoacyl-acyl carrier protein reductase, OXIDOREDUCTASE
Deposited on 2012-12-20, released 2013-01-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-01-09, with a file datestamp of 2013-01-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.218
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-ketoacyl-acyl carrier protein reductase (FabG)
    Species: Helicobacter pylori [TaxId:85962]
    Gene: HP0561, HP_0561
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25286 (24-270)
      • expression tag (23)
    Domains in SCOPe 2.05: d4iina_
  • Chain 'B':
    Compound: 3-ketoacyl-acyl carrier protein reductase (FabG)
    Species: Helicobacter pylori [TaxId:85962]
    Gene: HP0561, HP_0561
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25286 (24-270)
      • expression tag (23)
    Domains in SCOPe 2.05: d4iinb_
  • Chain 'C':
    Compound: 3-ketoacyl-acyl carrier protein reductase (FabG)
    Species: Helicobacter pylori [TaxId:85962]
    Gene: HP0561, HP_0561
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25286 (24-270)
      • expression tag (23)
    Domains in SCOPe 2.05: d4iinc_
  • Chain 'D':
    Compound: 3-ketoacyl-acyl carrier protein reductase (FabG)
    Species: Helicobacter pylori [TaxId:85962]
    Gene: HP0561, HP_0561
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25286 (24-270)
      • expression tag (23)
    Domains in SCOPe 2.05: d4iind_
  • Heterogens: NAD, K, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4iinA (A:)
    mhhhhhhssgvdlgtenlyfqsnamqftgknvlitgaskgigaeiaktlasmglkvwiny
    rsnaevadalkneleekgykaavikfdaasesdfieaiqtivqsdgglsylvnnagvvrd
    klaikmktedfhhvidnnltsafigcrealkvmsksrfgsvvnvasiigergnmgqtnys
    askggmiamsksfayegalrnirfnsvtpgfietdmnanlkdelkadyvkniplnrlgsa
    kevaeavafllsdhssyitgetlkvngglym
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iinA (A:)
    amqftgknvlitgaskgigaeiaktlasmglkvwinyrsnaevadalkneleekgykaav
    ikfdaasesdfieaiqtivqsdgglsylvnnagvvrdklaikmktedfhhvidnnltsaf
    igcrealkvmsksrfgsvvnvasiigergnmgqtnysaskggmiamsksfayegalrnir
    fnsvtpgfietdyvkniplnrlgsakevaeavafllsdhssyitgetlkvngglym
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4iinB (B:)
    mhhhhhhssgvdlgtenlyfqsnamqftgknvlitgaskgigaeiaktlasmglkvwiny
    rsnaevadalkneleekgykaavikfdaasesdfieaiqtivqsdgglsylvnnagvvrd
    klaikmktedfhhvidnnltsafigcrealkvmsksrfgsvvnvasiigergnmgqtnys
    askggmiamsksfayegalrnirfnsvtpgfietdmnanlkdelkadyvkniplnrlgsa
    kevaeavafllsdhssyitgetlkvngglym
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iinB (B:)
    amqftgknvlitgaskgigaeiaktlasmglkvwinyrsnaevadalkneleekgykaav
    ikfdaasesdfieaiqtivqsdgglsylvnnagvvrdklaikmktedfhhvidnnltsaf
    igcrealkvmsksrfgsvvnvasiigergnmgqtnysaskggmiamsksfayegalrnir
    fnsvtpgfietvkniplnrlgsakevaeavafllsdhssyitgetlkvngglym
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4iinC (C:)
    mhhhhhhssgvdlgtenlyfqsnamqftgknvlitgaskgigaeiaktlasmglkvwiny
    rsnaevadalkneleekgykaavikfdaasesdfieaiqtivqsdgglsylvnnagvvrd
    klaikmktedfhhvidnnltsafigcrealkvmsksrfgsvvnvasiigergnmgqtnys
    askggmiamsksfayegalrnirfnsvtpgfietdmnanlkdelkadyvkniplnrlgsa
    kevaeavafllsdhssyitgetlkvngglym
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iinC (C:)
    amqftgknvlitgaskgigaeiaktlasmglkvwinyrsnaevadalkneleekgykaav
    ikfdaasesdfieaiqtivqsdgglsylvnnagvvrdklaikmktedfhhvidnnltsaf
    igcrealkvmsksrfgsvvnvasiigergnmgqtnysaskggmiamsksfayegalrnir
    fnsvtpgfietkadyvkniplnrlgsakevaeavafllsdhssyitgetlkvngglym
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4iinD (D:)
    mhhhhhhssgvdlgtenlyfqsnamqftgknvlitgaskgigaeiaktlasmglkvwiny
    rsnaevadalkneleekgykaavikfdaasesdfieaiqtivqsdgglsylvnnagvvrd
    klaikmktedfhhvidnnltsafigcrealkvmsksrfgsvvnvasiigergnmgqtnys
    askggmiamsksfayegalrnirfnsvtpgfietdmnanlkdelkadyvkniplnrlgsa
    kevaeavafllsdhssyitgetlkvngglym
    

    Sequence, based on observed residues (ATOM records): (download)
    >4iinD (D:)
    amqftgknvlitgaskgigaeiaktlasmglkvwinyrsnaevadalkneleekgykaav
    ikfdaasesdfieaiqtivqsdgglsylvnnagvvrdklaikmktedfhhvidnnltsaf
    igcrealkvmsksrfgsvvnvasiigergnmgqtnysaskggmiamsksfayegalrnir
    fnsvtpgfietdyvkniplnrlgsakevaeavafllsdhssyitgetlkvngglym