PDB entry 4icc
View 4icc on RCSB PDB site
Description: Crystal structure of human AKR1B10 complexed with NADP+ and JF0064
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: TIM barrel, Aldo-Keto Reductase, Oxidoreductase, Halogenated compound, cytosolic, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2012-12-10, released
2014-02-19
The last revision prior to the SCOPe 2.06 freeze date was dated
2014-03-19, with a file datestamp of
2014-03-14.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.163
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'X':
Compound: Aldo-keto reductase family 1 member B10
Species: Homo sapiens [TaxId:9606]
Gene: AKR1B10, AKR1B11
Database cross-references and differences (RAF-indexed):
- Uniprot O60218 (0-315)
- engineered mutation (124)
- engineered mutation (300)
Domains in SCOPe 2.06: d4iccx_ - Heterogens: NAP, 64I, HOH