PDB entry 4iax

View 4iax on RCSB PDB site
Description: Engineered human lipocalin 2 (CL31) in complex with Y-DTPA
Class: transport protein
Keywords: beta-barrel, engineered lipocalin, binding protein, Y-CHX-A''-DTPA, Strep-tag, TRANSPORT PROTEIN
Deposited on 2012-12-07, released 2013-06-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-02-19, with a file datestamp of 2014-02-14.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.197
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Neutrophil gelatinase-associated lipocalin
  Species: Homo sapiens [TaxId:9606]
  Gene: HNL, LCN2, NGAL
  Database cross-references and differences (RAF-indexed):
  • Uniprot P80188
    • engineered mutation (27)
    • engineered mutation (32)
    • engineered mutation (35)
    • engineered mutation (40-43)
    • engineered mutation (45-51)
    • engineered mutation (53-54)
    • engineered mutation (64)
    • engineered mutation (67)
    • engineered mutation (69)
    • engineered mutation (74)
    • engineered mutation (76)
    • engineered mutation (78-80)
    • engineered mutation (85-86)
    • engineered mutation (98)
    • engineered mutation (106)
    • engineered mutation (126)
    • engineered mutation (133)
    • engineered mutation (135)
    • engineered mutation (137)
    • engineered mutation (144)
  Domains in SCOPe 2.07: d4iaxa_
• Heterogens: LIZ, YT3, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >4iaxA (A:)
  qdstsdlipapplskvplqqnfqdnqfhgkwyqvgragnaappmdpelllltaqtyelke
  dksydvtavrfrkkmceyltmtfvpspqpgeftlgniknypgltsyfvrvvstnynqham
  vffkkvqqnreyfsisllgrtkelaselkenfirfskslglpenhivfpvpidqcidgsa
  wshpqfek
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4iaxA (A:)
  dlipapplskvplqqnfqdnqfhgkwyqvgragnaappmdpelllltaqtyelkedksyd
  vtavrfrkkmceyltmtfvpspqpgeftlgniknypgltsyfvrvvstnynqhamvffkk
  vqqnreyfsisllgrtkelaselkenfirfskslglpenhivfpvpidqcid