PDB entry 4i91

View 4i91 on RCSB PDB site
Description: Crystal Structure of Cytochrome P450 2B6 (Y226H/K262R) in complex with alpha-Pinene.
Class: oxidoreductase
Keywords: Oxidoreductase, membrane protein, CYP2B6, P450, Cytochrome P450 2B6, Monooxygenase, Endoplasmic Reticulum, Heme, Iron, Membrane, Metal Binding, Microsome
Deposited on 2012-12-04, released 2013-07-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-12-31, with a file datestamp of 2014-12-26.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.183
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2B6
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2B6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20813 (Start-471)
      • engineered mutation (8-9)
      • engineered mutation (206)
      • engineered mutation (242)
      • expression tag (472)
    Domains in SCOPe 2.07: d4i91a1, d4i91a2
  • Heterogens: HEM, SUC, CM5, TMH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i91A (A:)
makktsskgklppgprplpllgnllqmdrrgllksflrfrekygdvftvhlgprpvvmlc
gveairealvdkaeafsgrgkiamvdpffrgygvifangnrwkvlrrfsvttmrdfgmgk
rsveeriqeeaqclieelrkskgalmdptflfqsitaniicsivfgkrfhyqdqeflkml
nlfyqtfslissvfgqlfelfsgflkhfpgahrqvyknlqeinayighsvekhretldps
aprdlidtyllhmekeksnahsefshqnlnlntlslffagtettsttlrygfllmlkyph
vaervyreieqvigphrppelhdrakmpyteaviyeiqrfsdllpmgvphivtqhtsfrg
yiipkdtevflilstalhdphyfekpdafnpdhfldangalkkteafipfslgkriclge
giaraelflffttilqnfsmaspvapedidltpqecgvgkipptyqirflprhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4i91A (A:)
gklppgprplpllgnllqmdrrgllksflrfrekygdvftvhlgprpvvmlcgveairea
lvdkaeafsgrgkiamvdpffrgygvifangnrwkvlrrfsvttmrdfgmgkrsveeriq
eeaqclieelrkskgalmdptflfqsitaniicsivfgkrfhyqdqeflkmlnlfyqtfs
lissvfgqlfelfsgflkhfpgahrqvyknlqeinayighsvekhretldpsaprdlidt
yllhmekeksnahsefshqnlnlntlslffagtettsttlrygfllmlkyphvaervyre
ieqvigphrppelhdrakmpyteaviyeiqrfsdllpmgvphivtqhtsfrgyiipkdte
vflilstalhdphyfekpdafnpdhfldangalkkteafipfslgkriclgegiaraelf
lffttilqnfsmaspvapedidltpqecgvgkipptyqirflprh