PDB entry 4i77
View 4i77 on RCSB PDB site
Description: Lebrikizumab Fab bound to IL-13
Class: immune system/cytokine
Keywords: immunoglobulin, immune system recognition, IMMUNE SYSTEM-CYTOKINE complex
Deposited on
2012-11-30, released
2013-02-06
The last revision prior to the SCOPe 2.03 freeze date was dated
2013-04-17, with a file datestamp of
2013-04-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.18
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Lebrikizumab heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: Lebrikizumab light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4i77l1, d4i77l2 - Chain 'Z':
Compound: interleukin-13
Species: Homo sapiens [TaxId:9606]
Gene: IL13, NC30
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4i77z_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'H':
No sequence available.
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>4i77L (L:)
divmtqspdslsvslgeratincrasksvdsygnsfmhwyqqkpgqppklliylasnles
gvpdrfsgsgsgtdftltisslqaedvavyycqqnnedprtfgggtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec
- Chain 'Z':
Sequence, based on SEQRES records: (download)
>4i77Z (Z:)
gpvppstalrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsaie
ktqrmlsgfcphkvsagqfsslhvrdtkievaqfvkdlllhlkklfregrfn
Sequence, based on observed residues (ATOM records): (download)
>4i77Z (Z:)
talrelieelvnitqplcngsmvwsinltagmycaaleslinvsgcsaiektqrmlsgfc
phkvsagqfsslhvrdtkievaqfvkdlllhlkklfr