PDB entry 4i75

View 4i75 on RCSB PDB site
Description: Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with the NiTris metalorganic complex
Class: hydrolase
Keywords: nucleoside hydrolase, open (alpha,beta) structure, NH fold, HYDROLASE
Deposited on 2012-11-30, released 2013-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-12-18, with a file datestamp of 2013-12-13.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.182
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inosine-adenosine-guanosine-nucleoside hydrolase
    Species: Trypanosoma brucei brucei [TaxId:999953]
    Gene: Tb927.3.2960
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57ZL6 (3-329)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d4i75a1, d4i75a2
  • Chain 'B':
    Compound: Inosine-adenosine-guanosine-nucleoside hydrolase
    Species: Trypanosoma brucei brucei [TaxId:999953]
    Gene: Tb927.3.2960
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4i75b_
  • Heterogens: CA, NI, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i75A (A:)
gshmaktvildhdgnkddfvamilllsnpkkvnligcictdadcfvengfdvtgkimcam
hrliktplfpigkstatavnafptewrfsaknlddmpflnivedvalweklkpeneahng
qqlladlvmkskekvtvcvtgplsnmawciekygeaftskveecvimggavdvggnvflp
ttdgsaewniywdppaakkvlccpnircvlfsldatntvpvrsvdvkgfgaqnqyllsqm
vgtmwamstheeilrdgdayyawdaltaayileptiatlepvaldvdvskgksegrtpra
sgegkpcvhvarnpskqmfhdlvfastrvc

    Sequence, based on observed residues (ATOM records): (download) 
    >4i75A (A:)
gshmaktvildhdgnkddfvamilllsnpkkvnligcictdadcfvengfdvtgkimcam
hrliktplfpigkstatavnafptewrfsaknlddmpflnivedvalweklkpeneahng
qqlladlvmkskekvtvcvtgplsnmawciekygeaftskveecvimggavdvggnvflp
ttdgsaewniywdppaakkvlccpnircvlfsldatntvpvrsvdvkgfgaqnqyllsqm
vgtmwamstheeilrdgdayyawdaltaayileptiatlepvaldvdvskgksegrtpra
pcvhvarnpskqmfhdlvfastrvc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i75B (B:)
gshmaktvildhdgnkddfvamilllsnpkkvnligcictdadcfvengfdvtgkimcam
hrliktplfpigkstatavnafptewrfsaknlddmpflnivedvalweklkpeneahng
qqlladlvmkskekvtvcvtgplsnmawciekygeaftskveecvimggavdvggnvflp
ttdgsaewniywdppaakkvlccpnircvlfsldatntvpvrsvdvkgfgaqnqyllsqm
vgtmwamstheeilrdgdayyawdaltaayileptiatlepvaldvdvskgksegrtpra
sgegkpcvhvarnpskqmfhdlvfastrvc

    Sequence, based on observed residues (ATOM records): (download) 
    >4i75B (B:)
maktvildhdgnkddfvamilllsnpkkvnligcictdadcfvengfdvtgkimcamhrl
iktplfpigkstatavnafptewrfsaknlddmpflnivedvalweklkpeneahngqql
ladlvmkskekvtvcvtgplsnmawciekygeaftskveecvimggavdvggnvflpttd
gsaewniywdppaakkvlccpnircvlfsldatntvpvrsvdvkgfgaqnqyllsqmvgt
mwamstheeilrdgdayyawdaltaayileptiatlepvaldvdvskgksegrtprapcv
hvarnpskqmfhdlvfastrvc