PDB entry 4i6a

View 4i6a on RCSB PDB site
Description: 3-hydroxy-3-methylglutaryl (HMG) Coenzyme A reductase from Pseudomonas mevalonii complexed with HMG-CoA
Class: Oxidoreductase
Keywords: Oxidoreductase
Deposited on 2012-11-29, released 2013-07-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-12-25, with a file datestamp of 2013-12-20.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.179
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4i6aa1, d4i6aa2
  • Chain 'B':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4i6ab1, d4i6ab2
  • Heterogens: HMG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i6aA (A:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4i6aA (A:)
ldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpy
avasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiq
dplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvr
damgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsge
aviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghyg
slttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgl
aqnlgamralategiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i6aB (B:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4i6aB (B:)
ldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpy
avasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiq
dplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvr
damgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsge
aviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghyg
slttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgl
aqnlgamralategiq