PDB entry 4i5x

View 4i5x on RCSB PDB site
Description: Crystal Structure Of AKR1B10 Complexed With NADP+ And Flufenamic acid
Class: oxidoreductase
Keywords: TIM barrel, aldo-keto reductase, Oxidoreductase
Deposited on 2012-11-29, released 2013-10-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-12-11, with a file datestamp of 2013-12-06.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.199
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member B10
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B10
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60218 (2-317)
      • expression tag (0-1)
      • see remark 999 (314)
    Domains in SCOPe 2.06: d4i5xa1, d4i5xa2
  • Heterogens: FLF, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4i5xA (A:)
ahmatfvelstkakmpivglgtwksplgkvkeavkvaidagyrhidcayvyqnehevgea
iqekiqekavkredlfivsklwptfferplvrkafektlkdlklsyldvylihwpqgfks
gddlfpkddkgnaiggkatfldaweameelvdeglvkalgvsnfshfqiekllnkpglky
kpvtnqvechpyltqekliqychskgitvtaysplgspdrpwakpedpslledpkikeia
akhkktaaqvlirfhiqrnvivipksvtpariveniqvfdfklsdeematilsfnrnwra
cnvlqsshledypfdaey