PDB entry 4i5e

View 4i5e on RCSB PDB site
Description: Crystal structure of Ralstonia sp. alcohol dehydrogenase in complex with NADP+
Class: oxidoreductase
Keywords: oxidoreductase, short-chain-dehydrogenases/reductases, Rossmann fold, Ralstonia sp., alcohol dehydrogenase, RasADH, cosubstrate specificity, NADH, S-phenylethanol
Deposited on 2012-11-28, released 2013-06-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-10-09, with a file datestamp of 2013-10-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.263
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5ea1, d4i5ea2
  • Chain 'B':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5eb1, d4i5eb2
  • Chain 'C':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5ec1, d4i5ec2
  • Chain 'D':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5ed1, d4i5ed2
  • Chain 'E':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5ee1, d4i5ee2
  • Chain 'F':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5ef1, d4i5ef2
  • Chain 'G':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5eg1, d4i5eg2
  • Chain 'H':
    Compound: Alclohol dehydrogenase/short-chain dehydrogenase
    Species: Ralstonia sp. [TaxId:517192]
    Gene: RasADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (14-261)
      • expression tag (13)
    Domains in SCOPe 2.08: d4i5eh1, d4i5eh2
  • Heterogens: NAP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i5eA (A:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eA (A:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i5eB (B:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eB (B:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4i5eC (C:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eC (C:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4i5eD (D:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eD (D:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4i5eE (E:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eE (E:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4i5eF (F:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eF (F:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4i5eG (G:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eG (G:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4i5eH (H:)
masrgshhhhhhgayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaa
aeigrnvtavkadvtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrt
fdvnvrgliftvqkalpllrdggsviltssvagvlglqahdtysaakaavrslartwtte
lkgrsirvnavspgaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlfl
asddssyvagielfvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4i5eH (H:)
ayrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaieqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpiienqvstqeeadelrakfaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv