PDB entry 4i4b

View 4i4b on RCSB PDB site
Description: HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2012-11-27, released 2013-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4i4ba1, d4i4ba2
  • Chain 'B':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4i4bb1, d4i4bb2
  • Heterogens: 1CV, GOL, SO4, NAD, 1CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i4bA (A:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4i4bA (A:)
ldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpy
avasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiq
dplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvr
damgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsge
aviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghyg
slttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgl
aqnlgamralategiqrghmalharniavvagarqlveyhdvradraval

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i4bB (B:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4i4bB (B:)
ldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpy
avasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiq
dplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvr
damgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsge
aviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghyg
slttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgl
aqnlgamralategiq