PDB entry 4i3z

View 4i3z on RCSB PDB site
Description: Structure of pCDK2/CyclinA bound to ADP and 2 Magnesium ions
Class: Transferase/Cell Cycle
Keywords: ADP and Magnesium binding, T160 Phosphorylation, Transferase-Cell Cycle complex
Deposited on 2012-11-27, released 2012-12-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-12-26, with a file datestamp of 2012-12-21.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.199
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4i3za_
  • Chain 'B':
    Compound: Cyclin-A2
    Species: Mus musculus [TaxId:10090]
    Gene: Ccna, Ccna2, Cyca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4i3zb1, d4i3zb2
  • Chain 'C':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4i3zc_
  • Chain 'D':
    Compound: Cyclin-A2
    Species: Mus musculus [TaxId:10090]
    Gene: Ccna, Ccna2, Cyca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4i3zd1, d4i3zd2
  • Heterogens: ADP, MG, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i3zA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i3zB (B:)
    vpdyqedihtylremevkckpkvgymkrqpditnsmrailvdwlvevgeeyklqnetlhl
    avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyskkqvlrm
    ehlvlkvlafdlaaptvnqfltqyflhlqpanckveslamflgelslidadpylkylpsl
    iagaafhlalytvtgqswpeslaqqtgytleslkpclvdlhqtylkapqhaqqsirekyk
    hskyhsvsllnppetls
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i3zC (C:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i3zD (D:)
    vpdyqedihtylremevkckpkvgymkrqpditnsmrailvdwlvevgeeyklqnetlhl
    avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyskkqvlrm
    ehlvlkvlafdlaaptvnqfltqyflhlqpanckveslamflgelslidadpylkylpsl
    iagaafhlalytvtgqswpeslaqqtgytleslkpclvdlhqtylkapqhaqqsirekyk
    hskyhsvsllnppetls