PDB entry 4i1n
View 4i1n on RCSB PDB site
Description: R104A-ca1697 nanobody binding to the binary DHFR.folate complex
Class: oxidoreductase/immune system
Keywords: alpha/beta fold, immunoglobulin fold, reductase, NADPH, folate derivatives, hydride transfer, OXIDOREDUCTASE-IMMUNE SYSTEM complex
Deposited on
2012-11-21, released
2013-11-27
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-11-27, with a file datestamp of
2013-11-22.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: 0.179
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:83333]
Gene: folA, tmrA, b0048, JW0047
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4i1na_ - Chain 'B':
Compound: Protein ca1697 (nanobody)
Species: Lama glama [TaxId:9844]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4i1nb_ - Heterogens: FOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4i1nA (A:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4i1nB (B:)
qvqlqesggglvqagaslrlscaaserltvdyaigwfrqapgkerefvaaiswgggltvy
gesvegrftisrdiakntmnlqmnvlrpedtanyycaasrisyavwntipynkltlwgrg
tqvtvsshhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4i1nB (B:)
qvqlqesggglvqagaslrlscaaserltvdyaigwfrqapgkerefvaaiswgggltvy
gesvegrftisrdiakntmnlqmnvlrpedtanyycaasrisyavwntipynkltlwgrg
tqvtvssh