PDB entry 4i13

View 4i13 on RCSB PDB site
Description: Nanobody ca1697 binding to the DHFR.folate binary complex
Class: oxidoreductase/immune system
Keywords: alpha/beta fold, immunoglobulin fold, reductase, NADPH, folate derivatives, reduction, OXIDOREDUCTASE-IMMUNE SYSTEM complex
Deposited on 2012-11-19, released 2013-11-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-11-27, with a file datestamp of 2013-11-22.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.155
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Escherichia coli [TaxId:83333]
    Gene: folA, tmrA, b0048, JW0047
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4i13a_
  • Chain 'B':
    Compound: Protein ca1697 (nanobody)
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4I13 (0-End)
    Domains in SCOPe 2.07: d4i13b1, d4i13b2
  • Heterogens: FOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i13A (A:)
    misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
    ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
    gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4i13B (B:)
    qvqlqesggglvqagaslrlscaaserltvdyaigwfrqapgkerefvaaiswgggltvy
    gesvegrftisrdiakntmnlqmnvlrpedtanyycaasrisyrvwntipynkltlwgrg
    tqvtvsshhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4i13B (B:)
    qvqlqesggglvqagaslrlscaaserltvdyaigwfrqapgkerefvaaiswgggltvy
    gesvegrftisrdiakntmnlqmnvlrpedtanyycaasrisyrvwntipynkltlwgrg
    tqvtvssh