PDB entry 4i08

View 4i08 on RCSB PDB site
Description: Crystal structure of beta-ketoacyl-acyl carrier protein reductase (FabG) from Vibrio cholerae in complex with NADPH
Class: oxidoreductase
Keywords: STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, Vibrio cholerae, FabG, Rossmann fold, beta-ketoacyl-acyl carrier protein reductase, short chain dehydrogenase, NADP(H), OXIDOREDUCTASE
Deposited on 2012-11-16, released 2012-12-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: Vibrio cholerae O1 [TaxId:243277]
    Gene: fabG, VC2021, VC_2021
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KQH7 (7-250)
      • expression tag (4-6)
    Domains in SCOPe 2.08: d4i08a1, d4i08a2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: Vibrio cholerae O1 [TaxId:243277]
    Gene: fabG, VC2021, VC_2021
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KQH7 (7-250)
      • expression tag (4-6)
    Domains in SCOPe 2.08: d4i08b1, d4i08b2
  • Heterogens: SO4, EDO, NDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i08A (A:)
snamsqfmnlegkvalvtgasrgigkaiaellaergakvigtatsesgaqaisdylgdng
kgmalnvtnpesieavlkaitdefggvdilvnnagitrdnllmrmkeeewsdimetnlts
ifrlskavlrgmmkkrqgriinvgsvvgtmgnagqanyaaakagvigftksmarevasrg
vtvntvapgfietdmtkalndeqrtatlaqvpagrlgdpreiasavaflaspeaayitge
tlhvnggmymi

    Sequence, based on observed residues (ATOM records): (download) 
    >4i08A (A:)
sqfmnlegkvalvtgasrgigkaiaellaergakvigtatsesgaqaisdylgdngkgma
lnvtnpesieavlkaitdefggvdilvnnagitrdnllmrmkeeewsdimetnltsifrl
skavlrgmmkkrqgriinvgsvvgtmgnagqanyaaakagvigftksmarevasrgvtvn
tvapgfietdmndeqrtatlaqvpagrlgdpreiasavaflaspeaayitgetlhvnggm
ymi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i08B (B:)
snamsqfmnlegkvalvtgasrgigkaiaellaergakvigtatsesgaqaisdylgdng
kgmalnvtnpesieavlkaitdefggvdilvnnagitrdnllmrmkeeewsdimetnlts
ifrlskavlrgmmkkrqgriinvgsvvgtmgnagqanyaaakagvigftksmarevasrg
vtvntvapgfietdmtkalndeqrtatlaqvpagrlgdpreiasavaflaspeaayitge
tlhvnggmymi

    Sequence, based on observed residues (ATOM records): (download) 
    >4i08B (B:)
sqfmnlegkvalvtgasrgigkaiaellaergakvigtatsesgaqaisdylgdngkgma
lnvtnpesieavlkaitdefggvdilvnnagitrdnllmrmkeeewsdimetnltsifrl
skavlrgmmkkrqgriinvgsvvgtmgnagqanyaaakagvigftksmarevasrgvtvn
tvapgfiettkalndeqrtatlaqvpagrlgdpreiasavaflaspeaayitgetlhvng
gmymi