PDB entry 4hzz

View 4hzz on RCSB PDB site
Description: Crystal structure of influenza neuraminidase N3-H274Y complexed with oseltamivir
Class: hydrolase/hydrolase inhibitor
Keywords: neuraminidase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-11-16, released 2013-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:489926]
    Gene: NA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9YN63 (0-386)
      • engineered mutation (193)
    Domains in SCOPe 2.08: d4hzza_
  • Heterogens: CA, G39, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hzzA (A:)
rpfksplplcpfrgffpfhkdnairlgenkdvivtrepyvscdndncwsfalaqgallgt
khsngtikdrtpyrslirfpigtapvlgnykeiciawsssscfdgkewmhvcmtgndnda
saqiiyggrmtdsikswrkdilrtqesecqcidgtcvvavtdgpaansadyrvywiregk
iikyenvpktkiqyleecscyvdidvycicrdnwkgsnrpwmrinnetiletgyvcskfh
sdtprpadpstmscdspsnvnggpgvkgfgfkagddvwlgrtvstsgrsgfeiikvtegw
inspnhvksitqtlvsnndwsgysgsfivkakdcfqpcfyvelirgrpnknddvswtsns
ivtfcgldnepgsgnwpdgsnigfmpk