PDB entry 4hx3

View 4hx3 on RCSB PDB site
Description: Crystal structure of Streptomyces caespitosus sermetstatin in complex with S. caespitosus snapalysin
Class: Hydrolase/Hydrolase Inhibitor
Keywords: Streptomyces subtilisin inhibitor fold, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2012-11-09, released 2012-12-05
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-02-27, with a file datestamp of 2013-02-22.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.196
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Extracellular small neutral protease
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: snpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56406 (3-133)
      • expression tag (0-2)
      • expression tag (1)
    Domains in SCOPe 2.05: d4hx3a_
  • Chain 'B':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4hx3b_
  • Chain 'C':
    Compound: Extracellular small neutral protease
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: snpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56406 (3-133)
      • expression tag (0-2)
      • expression tag (1)
    Domains in SCOPe 2.05: d4hx3c_
  • Chain 'D':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4hx3d_
  • Chain 'E':
    Compound: Extracellular small neutral protease
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: snpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56406 (3-133)
      • expression tag (2)
    Domains in SCOPe 2.05: d4hx3e_
  • Chain 'F':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4hx3f_
  • Chain 'G':
    Compound: Extracellular small neutral protease
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: snpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56406 (3-133)
      • expression tag (1-2)
      • expression tag (1)
    Domains in SCOPe 2.05: d4hx3g_
  • Chain 'H':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9FDS0 (1-113)
      • expression tag (0)
    Domains in SCOPe 2.05: d4hx3h_
  • Chain 'I':
    Compound: Extracellular small neutral protease
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: snpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56406 (3-133)
      • expression tag (0-2)
      • expression tag (1)
    Domains in SCOPe 2.05: d4hx3i_
  • Chain 'J':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4hx3j_
  • Chain 'K':
    Compound: Extracellular small neutral protease
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: snpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56406 (3-133)
      • expression tag (1-2)
      • expression tag (1)
    Domains in SCOPe 2.05: d4hx3k_
  • Chain 'L':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4hx3l_
  • Heterogens: ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hx3A (A:)
gpmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtd
ghgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypn
aqersrvnalwang

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4hx3B (B:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3B (B:)
sahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrll
aapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hx3C (C:)
gpmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtd
ghgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypn
aqersrvnalwang

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4hx3D (D:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3D (D:)
sahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrll
aalvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4hx3E (E:)
gpmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtd
ghgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypn
aqersrvnalwang

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3E (E:)
mvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtdgh
grgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypnaq
ersrvnalwang

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4hx3F (F:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3F (F:)
ahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrlla
apdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4hx3G (G:)
gpmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtd
ghgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypn
aqersrvnalwang

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3G (G:)
pmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtdg
hgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypna
qersrvnalwang

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4hx3H (H:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3H (H:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
llvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hx3I (I:)
gpmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtd
ghgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypn
aqersrvnalwang

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4hx3J (J:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3J (J:)
sahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrll
aapdpvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >4hx3K (K:)
gpmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtd
ghgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypn
aqersrvnalwang

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3K (K:)
pmvtvtydpsnapsfqqeianaaqiwnssvrnvqlraggnadfsyyegndsrgsyaqtdg
hgrgyifldyqqnqqydstrvtahetghvlglpdhyqgpcselmsgggpgpsctnpypna
qersrvnalwang

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4hx3L (L:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx3L (L:)
sahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrll
aapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf