PDB entry 4hx2

View 4hx2 on RCSB PDB site
Description: Crystal structure of Streptomyces caespitosus sermetstatin in complex with Bacillus licheniformis subtilisin
Class: Hydrolase/Hydrolase Inhibitor
Keywords: Streptomyces subtilisin inhibitor fold, Subtilisin Carlsberg, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2012-11-09, released 2012-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: KerA
    Species: Bacillus licheniformis [TaxId:1402]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4hx2a_
  • Chain 'B':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9FDS0 (1-113)
      • expression tag (0)
    Domains in SCOPe 2.08: d4hx2b1, d4hx2b2
  • Chain 'C':
    Compound: KerA
    Species: Bacillus licheniformis [TaxId:1402]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4hx2c_
  • Chain 'D':
    Compound: Neutral proteinase inhibitor ScNPI
    Species: Streptomyces caespitosus [TaxId:53502]
    Gene: ScNPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4hx2d_
  • Heterogens: CA, ZN, CL, 1AX, PO4, GOL, IPA, K, CAC, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hx2A (A:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgssgntntigypakydsviavgavd
snsnrasfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnl
sasqvrnrlsstatylgssfyygkglinveaaaq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hx2B (B:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hx2C (C:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgssgntntigypakydsviavgavd
snsnrasfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnl
sasqvrnrlsstatylgssfyygkglinveaaaq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4hx2D (D:)
gsahgpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrl
laapdpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf

    Sequence, based on observed residues (ATOM records): (download) 
    >4hx2D (D:)
gpsamvftviqgsgeptdtvlrattlscaytaegthpapraacdalnatdgelnrllaap
dpslvcpmyfdpvtvtadgvlngrrvawkhtfsntcvmsanlnsnpvyaf