PDB entry 4hth

View 4hth on RCSB PDB site
Description: Crystal structure of Staphylococcal nuclease variant Delta+VIAGLA at cryogenic temperature
Class: hydrolase
Keywords: nuclease, hyperstable, pdTp, HYDROLASE
Deposited on 2012-11-01, released 2012-11-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-11-28, with a file datestamp of 2012-11-23.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.177
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thermonuclease
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00644
      • engineered mutation (32)
      • engineered mutation (40)
      • engineered mutation (43-44)
      • engineered mutation (52)
      • engineered mutation (110)
      • engineered mutation (117)
      • engineered mutation (121)
    Domains in SCOPe 2.05: d4htha_
  • Heterogens: THP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4hthA (A:)
    atstkklhkepatlikaidgdtvklmykgqpmvfrlllvdipefnekygpeaaaftkkmv
    enakkievefdkgqrtdkygrglayiyadgkmvnealvrqglakvayvykgnntheqllr
    kaeaqakkeklniwsednadsgq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4hthA (A:)
    lhkepatlikaidgdtvklmykgqpmvfrlllvdipefnekygpeaaaftkkmvenakki
    evefdkgqrtdkygrglayiyadgkmvnealvrqglakvayvykgnntheqllrkaeaqa
    kkeklniws