PDB entry 4hsh

View 4hsh on RCSB PDB site
Description: tRNA-guanine transglycosylase Y106F, V233G mutant in complex with queuine
Class: Transferase/Transferase Inhibitor
Keywords: substrate specificity, bacterial TGT, transferase, guanine, preQ1, queuine, Transferase-Transferase Inhibitor complex
Deposited on 2012-10-30, released 2012-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-17, with a file datestamp of 2013-07-12.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: 0.157
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (104)
      • engineered mutation (231)
      • see remark 999 (310)
    Domains in SCOPe 2.07: d4hsha_
  • Heterogens: GOL, ZN, QEI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hshA (A:)
veataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvra
tgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmslssltkqseeg
vtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrwakr
srdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglaggegqdemf
rvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpin
irnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqki
rdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4hshA (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiilgn
tyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmstkqseegvtfkshrhmlspe
rsieiqhllgsdivmafdectpypatpsraassmersmrwakrsrdafdsrkeqaenaal
fgiqqgsvfenlrqqsadalaeigfdgyavgglaggegqdemfrvldfsvpmlpddkphy
lmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkpldsec
hcavcqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfr
aryfa