SCOPe 2.08: Structural Classification of Proteins

PDB entry 4hr7

View 4hr7 on RCSB PDB site
Description: Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli
Class: ligase/biotin binding protein
Keywords: biotin carboxylase, biotin carboxyl carrier protein, acetyl-CoA carboxylase, protein-protein interaction, protein complex, protein interface, antibiotic target, ATP grasp, biotin-dependent carboxylase, fatty acid synthesis, LIGASE-BIOTIN BINDING PROTEIN complex
Deposited on 2012-10-26, released 2013-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-05-29, with a file datestamp of 2013-05-24.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.197
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accC, fabG, b3256, JW3224
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (0-End)
Domains in SCOPe 2.08: d4hr7a1, d4hr7a2, d4hr7a3
Chain 'B':
Compound: Biotin carboxyl carrier protein of acetyl-CoA carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accB, fabE, b3255, JW3223
Database cross-references and differences (RAF-indexed):
- Uniprot P0ABD8 (Start-175)
Domains in SCOPe 2.08: d4hr7b_
Chain 'C':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accC, fabG, b3256, JW3224
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (0-End)
Domains in SCOPe 2.08: d4hr7c1, d4hr7c2, d4hr7c3
Chain 'D':
Compound: Biotin carboxyl carrier protein of acetyl-CoA carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accB, fabE, b3255, JW3223
Database cross-references and differences (RAF-indexed):
- Uniprot P0ABD8 (Start-175)
Domains in SCOPe 2.08: d4hr7d_
Chain 'E':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accC, fabG, b3256, JW3224
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (0-End)
Domains in SCOPe 2.08: d4hr7e1, d4hr7e2, d4hr7e3
Chain 'F':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accC, fabG, b3256, JW3224
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (0-End)
Domains in SCOPe 2.08: d4hr7f1, d4hr7f2, d4hr7f3
Chain 'G':
Compound: Biotin carboxyl carrier protein of acetyl-CoA carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accB, fabE, b3255, JW3223
Database cross-references and differences (RAF-indexed):
- Uniprot P0ABD8 (Start-175)
Domains in SCOPe 2.08: d4hr7g_
Chain 'I':
Compound: Biotin carboxyl carrier protein of acetyl-CoA carboxylase
Species: Escherichia coli [TaxId:83333]
Gene: accB, fabE, b3255, JW3223
Database cross-references and differences (RAF-indexed):
- Uniprot P0ABD8 (Start-175)
Domains in SCOPe 2.08: d4hr7i_
Heterogens: SO4, EDO, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4hr7A (A:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklglqek