PDB entry 4hqv

View 4hqv on RCSB PDB site
Description: tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with queuine
Class: Transferase/Transferase Inhibitor
Keywords: substrate specificity, bacterial TGT, transferase, guanine, preQ1, queuine, Transferase-Transferase Inhibitor complex
Deposited on 2012-10-26, released 2012-11-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-17, with a file datestamp of 2013-07-12.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: 0.177
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (104)
      • engineered mutation (156)
      • engineered mutation (231)
      • see remark 999 (310)
    Domains in SCOPe 2.06: d4hqva_
  • Heterogens: ZN, GOL, QEI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hqvA (A:)
veataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvra
tgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmslssltkqseeg
vtfkshldgsrhmlspersieiqhllgsdivmafdevtpypatpsraassmersmrwakr
srdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglaggegqdemf
rvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpin
irnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqki
rdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4hqvA (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiilgn
tyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmslssltkqseegvtfkshldg
srhmlspersieiqhllgsdivmafdevtpypatpsraassmersmrwakrsrdafdsrk
eqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglaggegqdemfrvldfsvpm
lpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsed
lkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrf
sqfaqdfraryfa