PDB entry 4hom

View 4hom on RCSB PDB site
Description: Crystal structure of porcine aminopeptidase-N complexed with substance P
Class: hydrolase
Keywords: zinc aminopeptidase, HYDROLASE
Deposited on 2012-10-22, released 2012-10-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-11-14, with a file datestamp of 2012-11-09.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.15
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aminopeptidase N
    Species: Sus scrofa [TaxId:9823]
    Gene: ANPEP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15145 (0-900)
      • conflict (19)
      • conflict (44)
      • expression tag (901)
    Domains in SCOPe 2.07: d4homa1, d4homa2, d4homa3, d4homa4, d4homa5
  • Chain 'B':
    Compound: Substance P
    Database cross-references and differences (RAF-indexed):
    • PDB 4HOM (0-10)
  • Heterogens: NAG, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4homA (A:)
    qskpwnryrlpttllpdsynvtlrpyltpnadglyifkgksivrflcqeptdviiihskk
    lnyttqghmvvlrgvgdsqvpeidrtelvelteylvvhlkgslqpghmyemesefqgela
    ddlagfyrseymegnvkkvlattqmqstdarksfpcfdepamkatfnitlihpnnltals
    nmppkgsstplaedpnwsvtefettpvmstyllayivsefqsvnetaqngvliriwarpn
    aiaeghgmyalnvtgpilnffanhyntsyplpksdqialpdfnagamenwglvtyrenal
    lfdpqsssisnkervvtviahelahqwfgnlvtlawwndlwlnegfasyveylgadhaep
    twnlkdlivpgdvyrvmavdalasshplttpaeevntpaqisemfdsisyskgasvirml
    snfltedlfkeglasylhafayqnttyldlwehlqkavdaqtsirlpdtvraimdrwtlq
    mgfpvitvdtktgnisqkhflldsesnvtrssafdylwivpissikngvmqdhywlrdvs
    qaqndlfktasddwvllnvnvtgyfqvnydednwrmiqhqlqtnlsvipvinraqviyds
    fnlatahmvpvtlaldntlflngekeympwqaalsslsyfslmfdrsevygpmkkylrkq
    veplfqhfetltknwterpenlmdqyseinaistacsnglpqcenlaktlfdqwmsdpen
    npihpnlrstiycnaiaqggqdqwdfawgqlqqaqlvneadklrsalacsnevwllnryl
    gytlnpdlirkqdatstinsiasnvigqplawdfvqsnwkklfqdygggsfsfsnliqgv
    trrfssefelqqleqfkknnmdvgfgsgtraleqalektkanikwvkenkevvlnwfieh
    sshhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4homA (A:)
    qskpwnryrlpttllpdsynvtlrpyltpnadglyifkgksivrflcqeptdviiihskk
    lnyttqghmvvlrgvgdsqvpeidrtelvelteylvvhlkgslqpghmyemesefqgela
    ddlagfyrseymegnvkkvlattqmqstdarksfpcfdepamkatfnitlihpnnltals
    nmppkgsstplaedpnwsvtefettpvmstyllayivsefqsvnetaqngvliriwarpn
    aiaeghgmyalnvtgpilnffanhyntsyplpksdqialpdfnagamenwglvtyrenal
    lfdpqsssisnkervvtviahelahqwfgnlvtlawwndlwlnegfasyveylgadhaep
    twnlkdlivpgdvyrvmavdalasshplttpaeevntpaqisemfdsisyskgasvirml
    snfltedlfkeglasylhafayqnttyldlwehlqkavdaqtsirlpdtvraimdrwtlq
    mgfpvitvdtktgnisqkhflldsesnvtrssafdylwivpissikngvmqdhywlrdvs
    qaqndlfktasddwvllnvnvtgyfqvnydednwrmiqhqlqtnlsvipvinraqviyds
    fnlatahmvpvtlaldntlflngekeympwqaalsslsyfslmfdrsevygpmkkylrkq
    veplfqhfetltknwterpenlmdqyseinaistacsnglpqcenlaktlfdqwmsdpen
    npihpnlrstiycnaiaqggqdqwdfawgqlqqaqlvneadklrsalacsnevwllnryl
    gytlnpdlirkqdatstinsiasnvigqplawdfvqsnwkklfqdygggsfsfsnliqgv
    trrfssefelqqleqfkknnmdvgfgsgtraleqalektkanikwvkenkevvlnwfieh
    ss
    

  • Chain 'B':
    No sequence available.