PDB entry 4hlw

View 4hlw on RCSB PDB site
Description: Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzoimidazole derivatives.
Class: transcription
Keywords: Nuclear Hormone Receptor, Androgen Binding Domain, Transcriptional factor, TRANSCRIPTION
Deposited on 2012-10-17, released 2013-01-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-02-27, with a file datestamp of 2013-02-22.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.177
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AR, DHTR, NR3C4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4hlwa_
  • Heterogens: TES, 17W, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hlwA (A:)
iegyecqpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalp
gfrnlhvddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysq
cvrmrhlsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriia
ckrknptscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqv
pkilsgkvkpiyfhtq

    Sequence, based on observed residues (ATOM records): (download) 
    >4hlwA (A:)
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiatscsrr
fyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiy
fhtq