PDB entry 4hls

View 4hls on RCSB PDB site
Description: Crystal structure of mutant rabbit PRP 121-230 (S170N)
Class: membrane protein
Keywords: prp, prion, membrane, MEMBRANE PROTEIN
Deposited on 2012-10-17, released 2013-05-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: 0.147
AEROSPACI score: 0.71 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: major prion protein
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: PRNP, PRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95211
      • engineered mutation (71)
    Domains in SCOPe 2.05: d4hlsa_
  • Chain 'B':
    Compound: major prion protein
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: PRNP, PRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95211 (Start-131)
      • engineered mutation (71)
    Domains in SCOPe 2.05: d4hlsb_
  • Heterogens: CL, NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hlsA (A:)
mgsshhhhhhssglvprgshmavvgglggymlgsamsrplihfgndyedryyrenmyryp
nqvyyrpvdqynnqnsfvhdcvnitvkqhtvttttkgenftetdikimervveqmcitqy
qqesqaayqraa

    Sequence, based on observed residues (ATOM records): (download) 
    >4hlsA (A:)
ggymlgsamsrplihfgndyedryyrenmyrypnqvyyrpvdqynnqnsfvhdcvnitvk
qhtvttttkgenftetdikimervveqmcitqyqqes

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4hlsB (B:)
mgsshhhhhhssglvprgshmavvgglggymlgsamsrplihfgndyedryyrenmyryp
nqvyyrpvdqynnqnsfvhdcvnitvkqhtvttttkgenftetdikimervveqmcitqy
qqesqaayqraa

    Sequence, based on observed residues (ATOM records): (download) 
    >4hlsB (B:)
ggymlgsamsrplihfgndyedryyrenmyrypnqvyyrpvdqynnqnsfvhdcvnitvk
qhtvttttkgenftetdikimervveqmcitqyqqesqaayqraa