PDB entry 4hjs
View 4hjs on RCSB PDB site
Description: Kinetic stabilization of transthyretin through covalent modification of K15 by (E)-N-(4-(4-hydroxy-3,5-dimethylstyryl)ethanesulfonamide
Class: hormone binding protein
Keywords: HORMONE BINDING PROTEIN, Thyroxine, retinol binding protein
Deposited on
2012-10-14, released
2013-12-04
The last revision prior to the SCOPe 2.06 freeze date was dated
2013-12-11, with a file datestamp of
2013-12-06.
Experiment type: XRAY
Resolution: 1.22 Å
R-factor: 0.192
AEROSPACI score: 0.7
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: PALB, TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4hjsa_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: PALB, TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4hjsb_ - Heterogens: 18J, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4hjsA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4hjsB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
Sequence, based on observed residues (ATOM records): (download)
>4hjsB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn