PDB entry 4hgk

View 4hgk on RCSB PDB site
Description: Shark IgNAR variable domain
Class: immune system
Keywords: Ig-fold, human albumin, IMMUNE SYSTEM
Deposited on 2012-10-08, released 2013-05-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 3.04 Å
R-factor: 0.239
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4hgka1, d4hgka2
  • Chain 'B':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4hgkb1, d4hgkb2
  • Chain 'C':
    Compound: shark V-NAR antibody
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed):
    • PDB 4HGK
    Domains in SCOPe 2.07: d4hgkc1, d4hgkc2
  • Chain 'D':
    Compound: shark V-NAR antibody
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed):
    • PDB 4HGK
    Domains in SCOPe 2.07: d4hgkd1, d4hgkd2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4hgkA (A:)
    dahksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesae
    ncdkslhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpev
    dvmctafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllp
    kldelrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltk
    vhtecchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempa
    dlpslaadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekc
    caaadphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvst
    ptlvevsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkcctes
    lvnrrpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkat
    keqlkavmddfaafvekcckaddketcfaeegkklvaasqaalgl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4hgkA (A:)
    ksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencd
    kslhtlfgdklctvatlgemadccakqepernecflqhkddnpnlprlvrpevdvmctaf
    hdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpkldelrd
    egkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvhtecch
    gdllecaddradlakyicenqdsissklkeccekpllekshciaevendempadlpslaa
    dfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaaadph
    ecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvstptlvevsrnl
    gkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvnrrpcfsa
    lev
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4hgkB (B:)
    dahksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesae
    ncdkslhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpev
    dvmctafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllp
    kldelrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltk
    vhtecchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempa
    dlpslaadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekc
    caaadphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvst
    ptlvevsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkcctes
    lvnrrpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkat
    keqlkavmddfaafvekcckaddketcfaeegkklvaasqaalgl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4hgkB (B:)
    ksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencd
    kslhtlfgdklctvemadccakqepernecflqhkddnpnlprlvrpevdvmctafhdne
    etflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpkldelrdegka
    ssakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvhtecchgdll
    ecaddradlakyicenqdsissklkeccekpllekshciaevendempadlpslaadfve
    skdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaaadphecya
    kvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptlvevsrnlg
    kvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvnrrpcfsal
    e
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4hgkC (C:)
    mgwsciilflvatatgahstrvdqtprtatretgesltincvltdtsyplystywyrknp
    gssnkeqisisgryvesvnkgtksfslrikdltvadsatyicramgtniwtgdgagtvlt
    vnhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4hgkC (C:)
    trvdqtprtatretgesltincvltdtsyplystywyrknpgssnkeqisisgryvesvn
    kgtksfslrikdltvadsatyicramgtniwtgdgagtvltvnh
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4hgkD (D:)
    mgwsciilflvatatgahstrvdqtprtatretgesltincvltdtsyplystywyrknp
    gssnkeqisisgryvesvnkgtksfslrikdltvadsatyicramgtniwtgdgagtvlt
    vnhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4hgkD (D:)
    trvdqtprtatretgesltincvltdtsyplystywyrknpgssnkeqisisgryvesvn
    kgtksfslrikdltvadsatyicramgtniwtgdgagtvltvnh