PDB entry 4hga

View 4hga on RCSB PDB site
Description: Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX
Class: chaperone/apoptosis
Keywords: histone chaperone, CHAPERONE-APOPTOSIS complex
Deposited on 2012-10-07, released 2012-11-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-09-10, with a file datestamp of 2014-09-05.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.21
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Death domain-associated protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: DAXX, BING2, DAP6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UER7 (6-End)
      • expression tag (3-5)
  • Chain 'B':
    Compound: Histone H3.3
    Species: Homo sapiens [TaxId:9606]
    Gene: H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4hgab_
  • Chain 'C':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4hgac_
  • Heterogens: PC4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4hgaB (B:)
martkqtarkstggkaprkqlatkaarksapstggvkkphryrpgtvalreirryqkste
llirklpfqrlvreiaqdfktdlrfqsaaigalqeaseaylvglfedtnlcaihakrvti
mpkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >4hgaB (B:)
pgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqsaaigalqeaseaylvg
lfedtnlcaihakrvtimpkdiqlarrirgera

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4hgaC (C:)
msgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4hgaC (C:)
qgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdv
vyalkrqgrtlygfg