PDB entry 4hfu

View 4hfu on RCSB PDB site
Description: Crystal structure of Fab 8M2 in complex with a H2N2 influenza virus hemagglutinin
Class: viral protein/immune system
Keywords: VIRAL PROTEIN/IMMUNE SYSTEM, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2012-10-05, released 2013-02-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.11 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:382813]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q67085 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d4hfua1, d4hfua2
  • Chain 'B':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:382813]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4hfub_
  • Chain 'H':
    Compound: Fab 8M2 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4HFU
    Domains in SCOPe 2.08: d4hfuh_
  • Chain 'L':
    Compound: Fab 8M2 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4HFU (0-End)
    Domains in SCOPe 2.08: d4hful1, d4hful2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hfuA (A:)
pgdqicigyhannstekvdtilernvtvthakdilekthngklcklngipplelgdcsia
gwllgnpecdrllsvpewsyimekenprdglcypgsfndyeelkyllssvkhfekvkilp
kdrwtqhtttggsracavsgnpsffrnmvwltkkgsdypvakgsynntsgeqmliiwgvh
hpndeteqrtlyqnvgtyvsvgtstlnkrstpeiatrpkvnglgsrmefswtlldmwdti
nfestgnliapeygfkiskrgssgimktegtlencetkcqtplgainttlpfhnvhplti
gecpryvkseklvlatglrnvpqiesr

    Sequence, based on observed residues (ATOM records): (download) 
    >4hfuA (A:)
pgdqicigyhannstekvdtilernvtvthakdilekthngklcklngipplelgdcsia
gwllgnpecdrllsvpewsyimekenprlcypgsfndyeelkyllssvkhfekvkilpkd
rwtqhtttggsracavsgnpsffrnmvwltkkgsdypvakgsynntsgeqmliiwgvhhp
ndeteqrtlyqnvgtyvsvgtstlnkrstpeiatrpkvnglgsrmefswtlldmwdtinf
estgnliapeygfkiskrgssgimktegtlencetkcqtplgainttlpfhnvhpltige
cpryvkseklvlatglrnvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4hfuB (B:)
glfgaiagfieggwqgmvdgwygyhhsndqgsgyaadkestqkafdgitnkvnsviekmn
tqfeavgkefsnlerrlenlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrmqlrdnvkelgngcfefyhkcddecmnsvkngtydypkyeeesklnrneik

    Sequence, based on observed residues (ATOM records): (download) 
    >4hfuB (B:)
glfgaiagfieggwqgmvdgwygyhhsndqgsgyaadkestqkafdgitnkvnsviekmn
tqfeavgkefsnlerrlenlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrmqlrdnvkelgngcfefyhkcddecmnsvkngtydypkyeeesklnrne

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4hfuH (H:)
evqlvesgadmkppgssvkvpckasgdtfssytitwvrqapgqglewmggitpifgspny
aqrfqdrviitadeststaymevsnlrsedtavyfcarvggewgsgryyldhwgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >4hfuH (H:)
vqlvesgadmkppgssvkvpckasgdtfssytitwvrqapgqglewmggitpifgspnya
qrfqdrviitadeststaymevsnlrsedtavyfcarvggewgsgryyldhwgqgtlvtv
ssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4hfuL (L:)
diqltqspaslsvspgeratlscrasqsvagnlawyqqkpgqaprlliygastratgipa
rfsgsgsgteftltitslqsedfavyycqqynnwppwtfgqgtkvdikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >4hfuL (L:)
diqltqspaslsvspgeratlscrasqsvagnlawyqqkpgqaprlliygastratgipa
rfsgsgsgteftltitslqsedfavyycqqynnwppwtfgqgtkvdikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrg