PDB entry 4h9n

View 4h9n on RCSB PDB site
Description: Complex structure 1 of DAXX/H3.3(sub5)/H4
Class: DNA binding protein/apoptosis
Keywords: histone chaperone, DNA BINDING PROTEIN-APOPTOSIS complex
Deposited on 2012-09-24, released 2012-10-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-10-10, with a file datestamp of 2012-10-05.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.19
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3.3
    Species: Homo sapiens [TaxId:9606]
    Gene: H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P84243
      • engineered mutation (95)
      • engineered mutation (98)
      • engineered mutation (101)
      • engineered mutation (110)
      • engineered mutation (119)
    Domains in SCOPe 2.08: d4h9na_
  • Chain 'B':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h9nb_
  • Chain 'C':
    Compound: Death domain-associated protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: DAXX, BING2, DAP6
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h9nA (A:)
artkqtarkstggkaprkqlatkaarksapstggvkkphryrpgtvalreirryqkstel
lirklpfqrlvreiaqdfktdlrfqsaaigalqeaaeaflvalfedtnlctihakrvtif
pkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >4h9nA (A:)
kphryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqsaaigalqeaa
eaflvalfedtnlctihakrvtifpkdiqlarrirger

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h9nB (B:)
sgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkv
flenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4h9nB (B:)
kvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrk
tvtamdvvyalkrqgrtlygfgg

  • Chain 'C':
    No sequence available.