PDB entry 4h1q

View 4h1q on RCSB PDB site
Description: Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor.
Class: HYDROLASE/HYDROLASE inhibitor
Keywords: HYDROLASE/TWIN INHIBITOR, Zincin-like, Gelatinase, Collagenase (Catalytic Domain), HYDROLASE-HYDROLASE inhibitor complex
Deposited on 2012-09-11, released 2013-04-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-05-01, with a file datestamp of 2013-04-26.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: 0.172
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Matrix metalloproteinase-9
  Species: Homo sapiens [TaxId:9606]
  Gene: CLG4B, MMP9
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14780 (0-104)
  • Uniprot P14780 (106-159)
    • engineered mutation (117)
  Domains in SCOPe 2.05: d4h1qa_
• Chain 'B':
  Compound: Matrix metalloproteinase-9
  Species: Homo sapiens [TaxId:9606]
  Gene: CLG4B, MMP9
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14780 (0-104)
  • Uniprot P14780 (106-159)
    • engineered mutation (117)
  Domains in SCOPe 2.05: d4h1qb_
• Heterogens: ZN, CA, 0XX, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4h1qA (A:)
  fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
  fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
  halgldhssvpealmypmyrftegpplhkddvngirhlyg
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4h1qB (B:)
  fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
  fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
  halgldhssvpealmypmyrftegpplhkddvngirhlyg