PDB entry 4h0y

View 4h0y on RCSB PDB site
Description: Crystal structure of NAD+-Ia(E380S)-actin complex
Class: toxin/structural protein
Keywords: ADP-ribosyltransferase, TOXIN-STRUCTURAL PROTEIN complex
Deposited on 2012-09-10, released 2013-02-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.22
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Iota toxin component Ia
    Species: Clostridium perfringens [TaxId:1502]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q46220 (5-417)
      • engineered mutation (384)
    Domains in SCOPe 2.07: d4h0ya1, d4h0ya2
  • Chain 'B':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: ACTA1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4h0yb1, d4h0yb2
  • Heterogens: NAD, PO4, EDO, CA, ATP, LAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4h0yA (A:)
    rgshmafierpedflkdkenaiqwekkeaerveknldtlekealelykkdseqisnysqt
    rqyfydyqiesnprekeyknlrnaisknkidkpinvyyfespekfafnkeirtenqneis
    lekfnelketiqdklfkqdgfkdvslyepgngdekptpllihlklpkntgmlpyinsndv
    ktlieqdysikidkivriviegkqyikaeasivnsldfkddvskgdlwgkenysdwsnkl
    tpneladvndymrggytainnylisngplnnpnpeldskvnnienalkltpipsnlivyr
    rsgpqefgltltspeydfnkienidafkekwegkvitypnfistsigsvnmsafakrkii
    lrinipkdspgaylsaipgyageysvllnhgskfkinkvdsykdgtvtklildatlin
    

    Sequence, based on observed residues (ATOM records): (download)
    >4h0yA (A:)
    afierpedflkdkenaiqwekkeaerveknldtlekealelykkdseqisnysqtrqyfy
    dyqiesnprekeyknlrnaisknkidkpinvyyfespekfafnkeirtenqneislekfn
    elketiqdklfkqdgfkdvslyepgngdekptpllihlklpkntgmlpyinsndvktlie
    qdysikidkivriviegkqyikaeasivnsldfkddvskgdlwgkenysdwsnkltpnel
    advndymrggytainnylisngplnnpnpeldskvnnienalkltpipsnlivyrrsgpq
    efgltltspeydfnkienidafkekwegkvitypnfistsigsvnmsafakrkiilrini
    pkdspgaylsaipgyageysvllnhgskfkinkvdsykdgtvtklildatlin
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4h0yB (B:)
    dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
    krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
    qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
    agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
    elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
    ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
    eydeagpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >4h0yB (B:)
    ttalvcdngsglvkagfagddapravfpsivgrkdsyvgdeaqskrgiltlkypiehgii
    tnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyvai
    qavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilter
    gysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerfr
    cpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqke
    italapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkc