PDB entry 4h0v

View 4h0v on RCSB PDB site
Description: Crystal structure of NAD+-Ia(E378S)-actin complex
Class: toxin/structural protein
Keywords: ADP-ribosyltransferase, TOXIN-STRUCTURAL PROTEIN complex
Deposited on 2012-09-10, released 2013-02-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.217
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Iota toxin component Ia
    Species: Clostridium perfringens [TaxId:1502]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q46220 (5-417)
      • engineered mutation (382)
    Domains in SCOPe 2.07: d4h0va1, d4h0va2
  • Chain 'B':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: ACTA1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4h0vb1, d4h0vb2
  • Heterogens: NAD, PO4, EDO, CA, ATP, LAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h0vA (A:)
rgshmafierpedflkdkenaiqwekkeaerveknldtlekealelykkdseqisnysqt
rqyfydyqiesnprekeyknlrnaisknkidkpinvyyfespekfafnkeirtenqneis
lekfnelketiqdklfkqdgfkdvslyepgngdekptpllihlklpkntgmlpyinsndv
ktlieqdysikidkivriviegkqyikaeasivnsldfkddvskgdlwgkenysdwsnkl
tpneladvndymrggytainnylisngplnnpnpeldskvnnienalkltpipsnlivyr
rsgpqefgltltspeydfnkienidafkekwegkvitypnfistsigsvnmsafakrkii
lrinipkdspgaylsaipgyagsyevllnhgskfkinkvdsykdgtvtklildatlin

    Sequence, based on observed residues (ATOM records): (download) 
    >4h0vA (A:)
afierpedflkdkenaiqwekkeaerveknldtlekealelykkdseqisnysqtrqyfy
dyqiesnprekeyknlrnaisknkidkpinvyyfespekfafnkeirtenqneislekfn
elketiqdklfkqdgfkdvslyepgngdekptpllihlklpkntgmlpyinsndvktlie
qdysikidkivriviegkqyikaeasivnsldfkddvskgdlwgkenysdwsnkltpnel
advndymrggytainnylisngplnnpnpeldskvnnienalkltpipsnlivyrrsgpq
efgltltspeydfnkienidafkekwegkvitypnfistsigsvnmsafakrkiilrini
pkdspgaylsaipgyagsyevllnhgskfkinkvdsykdgtvtklildatlin

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h0vB (B:)
dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
eydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4h0vB (B:)
ttalvcdngsglvkagfagddapravfpsivgryvgdeaqskrgiltlkypiehgiitnw
ddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyvaiqav
lslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkiltergys
fvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerfrcpe
tlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqkeita
lapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkc