PDB entry 4gzt

View 4gzt on RCSB PDB site
Description: N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate
Class: viral protein
Keywords: beta-propella, influenza virus, neuraminidase, hemagglutinin, hemadsorption, viral infection, viral protein
Deposited on 2012-09-06, released 2012-10-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-12-05, with a file datestamp of 2012-11-30.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: 0.193
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZT (Start-392)
    Domains in SCOPe 2.07: d4gzta_
  • Chain 'B':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZT (Start-392)
    Domains in SCOPe 2.07: d4gztb_
  • Chain 'C':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZT (Start-392)
    Domains in SCOPe 2.07: d4gztc_
  • Chain 'D':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZT (Start-392)
    Domains in SCOPe 2.07: d4gztd_
  • Heterogens: G39, NAG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gztA (A:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gztA (A:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4gztB (B:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gztB (B:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4gztC (C:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gztC (C:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4gztD (D:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gztD (D:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi