PDB entry 4gyh

View 4gyh on RCSB PDB site
Description: Structure of human thymidylate synthase at high salt conditions
Class: transferase
Keywords: Methyl transferase, TRANSFERASE
Deposited on 2012-09-05, released 2012-10-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-01-28, with a file datestamp of 2015-01-23.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.222
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: TYMS, TS, OK/SW-cl.29
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4gyha_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gyhA (A:)
mpvagselprrplppaaqerdaeprpphgelqylgqiqhilrcgvrkddrtgtgtlsvfg
mqaryslrdefpllttkrvfwkgvleellwfikgstnakelsskgvkiwdangsrdflds
lgfstreegdlgpvygfqwrhfgaeyrdmesdysgqgvdqlqrvidtiktnpddrriimc
awnprdlplmalppchalcqfyvvnselscqlyqrsgdmglgvpfniasyalltymiahi
tglkpgdfihtlgdahiylnhieplkiqlqreprpfpklrilrkvekiddfkaedfqieg
ynphptikmemavhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4gyhA (A:)
pphgelqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvl
eellwfikgstnakelsskgvgdlgpvygfqwrhfgaeyrdmesdysgqgvdqlqrvidt
iktnpddrriimcawnprdlplmalppchalcqfyvvnselscqlyqrsgdmglgvpfni
asyalltymiahitglkpgdfihtlgdahiylnhieplkiqlqreprpfpklrilrkvek
iddfkaedfqiegynphptikme