PDB entry 4gw6
View 4gw6 on RCSB PDB site
Description: HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: Integrase, DDE motif, allosteric inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2012-08-31, released
2013-05-01
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-06-19, with a file datestamp of
2013-06-14.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.199
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Gag-Pol polyprotein
Species: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) [TaxId:11698]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4gw6a_ - Heterogens: ARS, LF2, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4gw6A (A:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnkkrkggiggysagerivdiiatdiqtke
Sequence, based on observed residues (ATOM records): (download)
>4gw6A (A:)
dcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacwwagikqefgipesmnkelkkiigqvrdqaehlktavqmavfih
nkkrkgggysagerivdiiatdiq