PDB entry 4gv1

View 4gv1 on RCSB PDB site
Description: PKB alpha in complex with AZD5363
Class: transferase/transferase inhibitor
Keywords: protein kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-08-30, released 2013-02-27
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-03-27, with a file datestamp of 2013-03-22.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: 0.182
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RAC-alpha serine/threonine-protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKT1, PKB, RAC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31749 (3-End)
      • expression tag (2)
      • conflict (332)
    Domains in SCOPe 2.04: d4gv1a_
  • Heterogens: 0XZ, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gv1A (A:)
lgsrvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenr
vlqnsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsa
ldylhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapev
ledndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksll
sgllkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfde
eftaqmititppdqddsmecvdserrphfpqfdysassta

    Sequence, based on observed residues (ATOM records): (download) 
    >4gv1A (A:)
srvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvl
qnsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsald
ylhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevle
dndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsg
llkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeef
taqmititpsmecvdserrphfpqfdysas