PDB entry 4guk

View 4guk on RCSB PDB site
Description: New crystal form structure of human NCS1
Class: protein binding
Keywords: alpha, neuronal calcium sensor, PROTEIN BINDING
Deposited on 2012-08-29, released 2013-12-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-12-25, with a file datestamp of 2013-12-20.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.201
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: neuronal calcium sensor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FLUP, FREQ, NCS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62166 (5-187)
      • expression tag (188-189)
      • expression tag (181-182)
    Domains in SCOPe 2.06: d4guka1, d4guka2
  • Chain 'B':
    Compound: neuronal calcium sensor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FLUP, FREQ, NCS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62166 (Start-187)
      • expression tag (188)
      • expression tag (181-182)
    Domains in SCOPe 2.06: d4gukb1, d4gukb2
  • Chain 'C':
    Compound: neuronal calcium sensor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FLUP, FREQ, NCS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62166 (10-End)
      • initiating methionine (5)
      • expression tag (6-9)
      • expression tag (188)
    Domains in SCOPe 2.06: d4gukc1, d4gukc2
  • Chain 'D':
    Compound: neuronal calcium sensor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FLUP, FREQ, NCS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62166 (5-187)
      • expression tag (188-189)
      • expression tag (181-182)
    Domains in SCOPe 2.06: d4gukd1, d4gukd2
  • Heterogens: PG4, EDO, CA, NA, P3G, P2G, ALA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gukA (A:)
mgksnsklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgd
ptkfatfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrne
mldivdaiyqmvgntvelpeeentpekrvdrifammdknadgkltlqefqegskadpsiv
qalslydglv

    Sequence, based on observed residues (ATOM records): (download) 
    >4gukA (A:)
sklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgdptkfa
tfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrnemldiv
daiyqmvgntlpeeentpekrvdrifammdknadgkltlqefqegskadpsivqalslyd
glv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4gukB (B:)
mgksnsklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgd
ptkfatfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrne
mldivdaiyqmvgntvelpeeentpekrvdrifammdknadgkltlqefqegskadpsiv
qalslydglv

    Sequence, based on observed residues (ATOM records): (download) 
    >4gukB (B:)
klkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgdptkfat
fvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrnemldivd
aiyqmvglpeeentpekrvdrifammdknadgkltlqefqegskadpsivqalslydgl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4gukC (C:)
mgksnsklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgd
ptkfatfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrne
mldivdaiyqmvgntvelpeeentpekrvdrifammdknadgkltlqefqegskadpsiv
qalslydglv

    Sequence, based on observed residues (ATOM records): (download) 
    >4gukC (C:)
sklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgdptkfa
tfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrnemldiv
daiyqmvgntlpeeentpekrvdrifammdknadgkltlqefqegskadpsivqalslyd
gl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4gukD (D:)
mgksnsklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgd
ptkfatfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrne
mldivdaiyqmvgntvelpeeentpekrvdrifammdknadgkltlqefqegskadpsiv
qalslydglv

    Sequence, based on observed residues (ATOM records): (download) 
    >4gukD (D:)
sklkpevveeltrktyftekevqqwykgfikdcpsgqldaagfqkiykqffpfgdptkfa
tfvfnvfdenkdgriefsefiqalsvtsrgtldeklrwafklydldndgyitrnemldiv
daiyqmvlpeeentpekrvdrifammdknadgkltlqefqegskadpsivqalslydglv