PDB entry 4gtt
View 4gtt on RCSB PDB site
Description: Engineered RabGGTase in complex with BMS analogue 12
Class: transferase/transferase inhibitor
Keywords: protein prenylation, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2012-08-29, released
2012-10-24
The last revision prior to the SCOPe 2.04 freeze date was dated
2012-10-24, with a file datestamp of
2012-10-19.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.179
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Geranylgeranyl transferase type-2 subunit alpha
Species: Rattus norvegicus [TaxId:10116]
Gene: Rabggta, Ggta
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Geranylgeranyl transferase type-2 subunit beta
Species: Rattus norvegicus [TaxId:10116]
Gene: Rabggtb, Ggtb
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4gttb_ - Heterogens: ZN, CA, 7TQ, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4gttB (B:)
gtqqkdvtiksdapdtlllekhadyiasygskkddyeycmseylrmsgvywgltvmdlmg
qlhrmnkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvva
yvqslqkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggf
gcrpgseshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcy
swwvlaslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsll
geeqikpvspvfcmpeevlqrvnvqpelvs
Sequence, based on observed residues (ATOM records): (download)
>4gttB (B:)
qkdvtiksdapdtlllekhadyiasygsdyeycmseylrmsgvywgltvmdlmgqlhrmn
keeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqslq
kedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpgs
eshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvla
slkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqik
pvspvfcmpeevlqrvnvqpelvs