PDB entry 4grz
View 4grz on RCSB PDB site
Description: Crystal structure of SHP1 catalytic domain with PO4
Class: hydrolase
Keywords: Phosphatase domain, Hydrolase
Deposited on
2012-08-27, released
2012-12-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-15, with a file datestamp of
2017-11-10.
Experiment type: XRAY
Resolution: 1.37 Å
R-factor: N/A
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tyrosine-protein phosphatase non-receptor type 6
Species: Homo sapiens [TaxId:9606]
Gene: HCP, PTP1C, PTPN6, SHP-1
Database cross-references and differences (RAF-indexed):
- Uniprot P29350 (2-End)
- engineered mutation (212)
Domains in SCOPe 2.08: d4grza_ - Heterogens: PO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4grzA (A:)
gsgfweefeslqkqevknlhqrlegqrpenkgknryknilpfdhsrvilqgrdsnipgsd
yinanyiknqllgpdenaktyiasqgcleatvndfwqmawqensrvivmttrevekgrnk
cvpywpevgmqraygpysvtncgehdtteyklrtlqvspldngdlireiwhyqylswpdh
gvpsepggvlsfldqinqrqeslphagpiivhssagigrtgtiividmlmenistkgldc
didiqktiqmvraqrsgmvqteaqykfiyvaiaqfiettkkklevlqs
Sequence, based on observed residues (ATOM records): (download)
>4grzA (A:)
gfweefeslqkqevknlhqrlegqrpenkgknryknilpfdhsrvilqgrdsnipgsdyi
nanyiknqllgpdenaktyiasqgcleatvndfwqmawqensrvivmttrevekgrnkcv
pywpevgmqraygpysvtncgehdtteyklrtlqvspldngdlireiwhyqylswpdhgv
psepggvlsfldqinqrqeslphagpiivhssagigrtgtiividmlmenistkgldcdi
diqktiqmvraqrsgmvqteaqykfiyvaiaqfiettkkkle