PDB entry 4grn

View 4grn on RCSB PDB site
Description: crystal structure of PAAM mutant of human MIF
Class: cytokine, Isomerase
Keywords: alpha/beta mixture, cytokine and enzyme, cytokine, Isomerase
Deposited on 2012-08-26, released 2013-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: macrophage migration inhibitory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: GLIF, human, MIF, MMIF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14174 (0-115)
      • insertion (1-2)
    Domains in SCOPe 2.08: d4grna_
  • Chain 'B':
    Compound: macrophage migration inhibitory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: GLIF, human, MIF, MMIF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14174 (0-115)
      • insertion (1-2)
    Domains in SCOPe 2.08: d4grnb_
  • Chain 'C':
    Compound: macrophage migration inhibitory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: GLIF, human, MIF, MMIF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14174 (0-115)
      • insertion (1-2)
    Domains in SCOPe 2.08: d4grnc_
  • Heterogens: CL, SO4, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4grnA (A:)
    paamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcal
    cslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4grnB (B:)
    paamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcal
    cslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4grnC (C:)
    paamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcal
    cslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa