PDB entry 4gjf

View 4gjf on RCSB PDB site
Description: Crystal structure of the amino-terminal domain of human cardiac troponin C mutant L29Q in complex with cadmium
Class: contractile protein
Keywords: helix-loop-helix ef-hand motif, contractile protein, calcium sensor, cadmium binding
Deposited on 2012-08-09, released 2013-02-06
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.143
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: troponin c, slow skeletal and cardiac muscles
    Species: Homo sapiens [TaxId:9606]
    Gene: TNNC, TNNC1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63316 (0-88)
      • engineered mutation (28)
    Domains in SCOPe 2.04: d4gjfa_
  • Heterogens: CA, CD, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4gjfA (A:)
    mddiykaaveqlteeqknefkaafdifvqgaedgcistkelgkvmrmlgqnptpeelqem
    idevdedgsgtvdfdeflvmmvrcmkdds
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gjfA (A:)
    mddiykaaveqlteeqknefkaafdifvqgaedgcistkelgkvmrmlgqnptpeelqem
    idevdegtvdfdeflvmmvrcmkdds