PDB entry 4gcx

View 4gcx on RCSB PDB site
Description: tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with preQ1
Class: transferase
Keywords: substrate specifity, bacterial TGT, transferase, tRNA, preQ1, guanine exchange enzyme
Deposited on 2012-07-31, released 2012-08-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-17, with a file datestamp of 2013-07-12.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: 0.134
AEROSPACI score: 0.72 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (105)
      • engineered mutation (157)
      • engineered mutation (232)
      • see remark 999 (311)
    Domains in SCOPe 2.06: d4gcxa_
  • Heterogens: PRF, ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gcxA (A:)
mveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvr
atgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmslssltkqsee
gvtfkshldgsrhmlspersieiqhllgsdivmafdevtpypatpsraassmersmrwak
rsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglaggegqdem
frvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpi
nirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqk
irdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4gcxA (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiilgn
tyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmstkqseegvtfkshldgsrhm
lspersieiqhllgsdivmafdevtpypatpsraassmersmrwakrsrdafdsrkeqae
naalfgiqqgsvfenlrqqsadalaeigfdgyavgglaggegqdemfrvldfsvpmlpdd
kphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkpl
dsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfa
qdfraryfa