PDB entry 4gb2
View 4gb2 on RCSB PDB site
Description: HIV-1 protease (mutant Q7K L33I L63I) in complex with a bicyclic pyrrolidine inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: Dimer, ASPARTYL PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2012-07-26, released
2013-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-07-31, with a file datestamp of
2013-07-26.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: 0.176
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Gag-Pol polyprotein
Species: Human immunodeficiency virus type 1 (BRU ISOLATE) [TaxId:11686]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
- Uniprot P03367 (0-98)
- engineered mutation (6)
- engineered mutation (32)
- engineered mutation (62)
Domains in SCOPe 2.08: d4gb2a_ - Chain 'B':
Compound: Gag-Pol polyprotein
Species: Human immunodeficiency virus type 1 (BRU ISOLATE) [TaxId:11686]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
- Uniprot P03367 (0-98)
- engineered mutation (6)
- engineered mutation (32)
- engineered mutation (62)
Domains in SCOPe 2.08: d4gb2b_ - Heterogens: CL, GOL, 0LQ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4gb2A (A:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieicghkaigtvlvgptpvniigrnlltqigctlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4gb2B (B:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieicghkaigtvlvgptpvniigrnlltqigctlnf