PDB entry 4g4o

View 4g4o on RCSB PDB site
Description: MutM containing M77A mutation bound to oxoG-containing DNA
Class: Hydrolase/DNA
Keywords: DNA glycosylase, DNA repair, lesion recognition, base extrusion, disulfide crosslinking, Hydrolase-DNA complex
Deposited on 2012-07-16, released 2013-02-20
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-04-24, with a file datestamp of 2013-04-19.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.177
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: formamidopyrimidine-DNA glycosylase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Gene: mutM
    Database cross-references and differences (RAF-indexed):
    • Uniprot P84131 (0-272)
      • engineered mutation (75)
      • engineered mutation (164)
    Domains in SCOPe 2.05: d4g4oa1, d4g4oa2, d4g4oa3
  • Chain 'B':
    Compound: DNA (5'-d(p*ap*gp*gp*tp*ap*gp*ap*cp*tp*cp*gp*gp*ap*cp*gp*c)-3')
  • Chain 'C':
    Compound: DNA (5'-d(*tp*gp*cp*gp*tp*cp*cp*(8og)p*ap*gp*(tx2)p*cp*tp*ap*cp*c)-3')
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4g4oA (A:)
pqlpevetirrtllplivgktiedvrifwpniirhprdseafaarmigqtvrglerrgkf
lkflldrdalishlraegryavasaleplephthvvfcftdgselryrdvrkfgtmhvya
keeadrrpplaelgpeplspafspavlaeravktkrsvkallldctvvagfgniyvdesl
fragilpgrpaaslsskeierlheemvatigeavmkggstvrtyvntqgeagtfqhhlyv
ygrqgnpckrcgtpiektvvagrgthycprcqr

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4oA (A:)
pqlpevetirrtllplivgktiedvrifwpniirhprdseafaarmigqtvrglerrgkf
lkflldrdalishlraegryavasaleplephthvvfcftdgselryrdvrkfgtmhvya
keeadrrpplaelgpeplspafspavlaeravktkrsvkallldctvvagfgniyvdesl
fragilpgrpaaslsskeierlheemvatigeavmhlyvygrqgnpckrcgtpiektvva
grgthycprcqr

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.